Indoles and derivatives

Aromatic bicyclic organic compounds that consists of a benzene ring fused to a pyrrole ring with formula: C₈H₇N.

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1,621 – 1,635 of 5,968 results

1,621

Medchemexpress LLC PD-1/PD-L1-IN-NP19 5mg

PD-1/PD-L1-IN-NP19 5mg

Pricing & Availability

1,622

eMolecules 2229974-83-6 | Medchem Express | XY028-140 | 5mg | 602878458 | HY-138946 | 760.812 | C39H40N10O7

Ambeed | 2-Chloro-1-fluoro-4-isocyanatobenzene | 1g | 569097108 | A935633 | 50529-33-4 | MFCD00037037 | 171.560 | C7H3ClFNO

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1,623

Medchemexpress LLC Erenapurstat | 136164-66-4 | 99.67% | 378.46 | 50 MG

Erenapurstat (E3330) is a direct, orally active and selective inhibitor of Ape-1 (apurinic/apyrimidinic endonuclease 1)/Ref-1 (redox factor-1) redox. It impairs tumor growth and blocks the activity of NF-κB, AP-1, and HIF-1α in pancreatic cancer, showing anticancer activities.

Targets Ape-1 and Ref-1
Inhibits growth of HUVECs, PCECs, and EPCs
Reduces VEGF expression in pancreatic cancer cells
Inhibits differentiation of BM-MSCs into CD31+ endothelial lineage cells
Decreases cell viability in H1975 cells
Inhibits growth and migration of pancreatic cancer cells
Enhances intracellular ROS level and inhibits CD44 expression in PANC1 cells
Neuroprotective against cisplatin-induced alterations
Attenuates liver injury in rats

Pricing & Availability

1,624

eMolecules 850623-66-4 | Potassium trifluoro(4-isobutylphenyl)borate | Ambeed | MFCD04115761 | 240.120 | C10H13BF3K | 98.000 | [K+].CC(C)Cc1ccc(cc1)[B-](F)(F)F | 1g | 586036590

Potassium trifluoro(4-isobutylphenyl)borate | Ambeed | 850623-66-4 | MFCD04115761 | 240.120 | C10H13BF3K | 98.000 | [K+].CC(C)Cc1ccc(cc1)[B-](F)(F)F | 1g | 586036590

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1,625

Medchemexpress LLC Tryptamine guanosine carbamate | 1414808-96-0 | 99.8% | 469.45 g·mol⁻¹ | C21H23N7O6 | 5 MG

Tryptamine guanosine carbamate is a small-molecule research compound that selectively inhibits HINT1 (histidine triad nucleotide-binding protein 1). It has been reported to enhance morphine antinociception while reducing development of tolerance, making it useful for biochemical and pharmacological studies.

Selective HINT1 inhibitor (Ki = 34 μM; Kd = 3.65 μM).
Molecular formula C21H23N7O6.
Molecular weight 469.45 g·mol⁻¹.
Purity 99.79% (reported).
Soluble in DMSO.
Available in small pack sizes, including 5 mg.
Applications include HINT1 signaling studies and opioid pharmacology research.

Pricing & Availability

1,626

Medchemexpress LLC 4'-acetyl-N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-[1,1'-biphenyl]-4-carboxamide | 162408-66-4 | 99.6% | 485.62 | C30H35N3O3 | 100 MG

A potent, selective dopamine D3 receptor antagonist used for receptor pharmacology research. It shows sub-nanomolar affinity for the D3 receptor and strong selectivity versus related dopamine subtypes.

Potent dopamine D3 receptor antagonist with Ki 0.4 nM.
Greater than 100-fold selectivity for D3 over D4 and D1.
High purity (batch COA: 99.6%).
White to off-white solid powder; molecular formula C30H35N3O3; molecular weight 485.62.
Suitable for in vitro and in vivo receptor pharmacology studies.
Store powder at -20°C; in solution store at -80°C for long-term stability.

Pricing & Availability

1,627

eMolecules 1379324-66-9 | 2-CHLOROBENZO[D]THIAZOLE-7-CARBOXYLIC ACID | AstaTech | MFCD13195420 | 213.640 | C8H4ClNO2S | 95.000 | OC(=O)c1cccc2nc(Cl)sc12 | 0.25g | 233628241

2-CHLOROBENZO[D]THIAZOLE-7-CARBOXYLIC ACID | AstaTech | 1379324-66-9 | MFCD13195420 | 213.640 | C8H4ClNO2S | 95.000 | OC(=O)c1cccc2nc(Cl)sc12 | 0.25g | 233628241

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1,628

Medchemexpress LLC Dicentrine | 517-66-8 | 5 MG

Dicentrine is a natural product isolated from the plant Stephania epigaea Lo that exhibits an antihypertensive effect. It functions as an α1-adrenoceptor antagonist and has been shown to be effective against human hyperplastic prostates.

Isolated from the plant Stephania epigaea Lo.
Exhibits an antihypertensive effect.
Functions as an α1-adrenoceptor antagonist.
Effective against human hyperplastic prostates.
For research use only.
High purity (99.94%).

Pricing & Availability

1,629

Medchemexpress LLC TAO Kinase inhibitor 1 | 850467-66-2 | 99.8% | 384.47 | 100 MG

TAO Kinase inhibitor 1 (compound 43) is a selective, ATP-competitive thousand-and-one amino acid kinases (TAOK) inhibitor with IC50s of 11 to 15 nM for TAOK1 and 2. It delays mitosis and induces mitotic cell death. It is for research use only.

Selective, ATP-competitive TAOK inhibitor.
IC50s of 11 to 15 nM for TAOK1 and 2.
Delays mitosis.
Induces mitotic cell death.
Purity: 99.81%.

Pricing & Availability

1,630

Chem-Impex International, Inc. 2-(2-Methyl-1H-indol-3-yl)ethylamine | 2731-06-8 | MFCD00130185 | 1G

2-(2-Methyl-1H-indol-3-yl)ethylamine, 2731-06-8, MFCD00130185, 1G

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1,631

Medchemexpress LLC DX3-213B | 2749555-66-4 | 99.7% | C20H28F2N2O5S2 | 100 MG

DX3-213B is a highly potent, orally active oxidative phosphorylation (OXPHOS) complex I inhibitor with an IC50 of 3.6 nM. It effectively impairs ATP generation with an IC50 of 11 nM and blocks the growth of MIA PaCa-2 cells, also with a GI50 of 11 nM. This compound is utilized in research concerning pancreatic cancer.

Highly potent and orally active.
Functions as an oxidative phosphorylation (OXPHOS) complex I inhibitor.
Impairs ATP generation.
Blocks MIA PaCa-2 cell growth.
Used in pancreatic cancer research.

Pricing & Availability

1,632

eMolecules 155877-83-1 | Medchem Express | LE135 | 5mg | 596366425 | HY-107436 | MFCD06798318 | 438.571 | C29H30N2O2

Ambeed | (S)-tert-Butyl 2-aminopropanoate | 1g | 572830027 | A605887 | 21691-50-9 | MFCD00270591 | 145.202 | C7H15NO2

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1,633

eMolecules 370882-66-9 | tert-butyl (1S,5R)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate | Pharmablock198.266 | C10H18N2O2 | 97.000 | CC(C)(C)OC(=O)N1C[C@@H]2CNC[C@H]12 | 25mg | 586144518

tert-butyl (1S,5R)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate | Pharmablock | 370882-66-9198.266 | C10H18N2O2 | 97.000 | CC(C)(C)OC(=O)N1C[C@@H]2CNC[C@H]12 | 25mg | 586144518

Pricing & Availability

1,634

Medchemexpress LLC Nevadensin | 10176-66-6 | MFCD08689947 | 344.32 | 20 MG

Nevadensin is a natural flavonoid and a selective human carboxylesterase 1 (hCE1) inhibitor. It demonstrates greater selectivity for hCE1 over hCE2.

Induces apoptosis and DNA damage in cancer cells.
Possesses anti-inflammatory, anti-tumor, anti-hypertensive, anti-tubercular, antitussive, antioxidant, and anti-microbial activities.
Inhibits hCE1 with an IC50 of 2.64 μM.

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1,635

Medchemexpress LLC Parp-2-in-1 | 2115698-83-2 | 99.6% | 465.40 g·mol⁻¹ | C21H19F4N5O3 | 10 MG

PARP-2-IN-1 is a potent, selective inhibitor of poly(ADP-ribose) polymerase 2 (PARP-2) used in research on DNA damage response and programmed cell death. It exhibits an IC50 of 11.5 nM against PARP-2 and is supplied as a high-purity small-molecule reagent for laboratory studies.

Potent and selective PARP-2 inhibition (IC50 11.5 nM).
High purity suitable for research (>99.5% by HPLC).
Well-characterized molecular properties (C21H19F4N5O3, 465.40 g·mol⁻¹).
Available in small mg-scale quantities for laboratory research.
Suitable for biochemical and cell-based assays studying DNA repair and apoptosis.
Provided with product datasheet and analytical data.

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Indoles and derivatives

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Medchemexpress LLC PD-1/PD-L1-IN-NP19 5mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Erenapurstat | 136164-66-4 | 99.67% | 378.46 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tryptamine guanosine carbamate | 1414808-96-0 | 99.8% | 469.45 g·mol⁻¹ | C21H23N7O6 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 4'-acetyl-N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-[1,1'-biphenyl]-4-carboxamide | 162408-66-4 | 99.6% | 485.62 | C30H35N3O3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dicentrine | 517-66-8 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC TAO Kinase inhibitor 1 | 850467-66-2 | 99.8% | 384.47 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC DX3-213B | 2749555-66-4 | 99.7% | C20H28F2N2O5S2 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nevadensin | 10176-66-6 | MFCD08689947 | 344.32 | 20 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Parp-2-in-1 | 2115698-83-2 | 99.6% | 465.40 g·mol⁻¹ | C21H19F4N5O3 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More